Principal Investigator
Division of Pediatrics
Digestive System Department
Division of General Internal Medicine
更新時間:2023-09-19
- Principal Investigator
- Clinical Trial Experience (year) 17 years 9 個月
Highlights
− Inflammatory Bowel Disease (IBD)
− Crohn's Disease
− Nutrition therapy microbiota
− Crohn's disease exclusion diet
2. Study to Evaluate Efficacy and Safety of MS-20 on Patients with Ulcerative Colitis
− Ulcerative colitis
− MS-20
3. Minimize the Risk of Infection-Related Cancers by Implementation of Microbiota Reprogramming
− HBV
− HIV
− HPV
− nasopharngeal carcinoma
− microbiology
4. Development of novel anti-allergic probiotics by gut microbiota metagenomic analysis in infant cohorts
− Allergic diseases
− Gut microbiota
− metabolites
− Prebiotics
− Probiotics
5. A Phase 3 Randomized, Open-Label Study to Assess the Efficacy, Safety, and
Pharmacokinetics of Golimumab Treatment, a Human anti-TNFα Monoclonal Antibody, Administered Subcutaneously in Pediatric Participants with Moderately to Severely Active Ulcerative Colitis
− Ulcerative colitis
− Pediatric
6. Explore the biomarkers determining the evolution of liver fibrosis and the outcome of pediatric chronic liver disease
− Microbiota
7. Gut microbiota play a critical role in determining the age-dependent outcome of hepatitis B virus infection
− Microbiota
8. The oncofetal RBMY protein and gut microbiota dysbiosis facilitate the development and metastasis of hepatocellular carcinoma
− Hepatocellular Carcinoma (HCC)
− Metastasis
− microbiota
− Epithelial–Mesenchymal Transition
9. Explore the clinical impacts of cell-free DNA as a noninvasive diagnosis of liver injury in pediatric liver transplant patients
− Liver transplant
10. Development of precision microbiome-based interventions in chronic hepatitis B
− Chronic hepatitis B
− Gut microbiota
Study Area
- Pediatric Liver Diseases: Viral Hepatitis and NAFLD
- Ulcerative Colitis
- Crohn's Disease
- Wilson Disease
- Obesity
Professional Experiences
Dean
College of Medicine
2019- 迄今
Distinguished Professor
Department of Pediatrics, College of Medicine
2016- 迄今
Professor (joint appointment)
Graduate Institute of Clinical Medicine, College of Medicine
2017- 迄今
Attending Physician
Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics
Education
Graduate Institute of Clinical Medicine
Ph.D.
1992-1997
School of Medicine, College of Medicine
M.D.
1979-1986
Clinical Trials List
2016
Total 64
-
I 0
-
I/II 0
-
II 20
-
II/III 7
-
III 37
-
IV 0
-
Others 0
Number of Studies by Scale
0件
Taiwan Multiple Center
Taiwan Single Center
0Cases
Taiwan Multiple Center
0Cases
Multi-Regional Multi-Center
60Cases