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Principal Investigator


Linkou Chang Gung Medical Foundation (在職)

Division of Orthopedics

更新時間:2023-09-19

張毓翰Chang, Yu-Han
  • Principal Investigator
  • Clinical Trial Experience (year) 23 years 9 個月
  • yhchang@cgmh.org.tw

Publication

21Publications

11

Chen MJ, Hung JF, Chang CH, Lee SH, Shih HN, Chang YH*. Periprosthetic knee infection reconstruction with a hinged prosthesis: Implant survival and risk factors for treatment failure. Knee. 2020 Jun; 27(3):1035-1042. (SCI, IF: 2.199, Orthopedics, Rank: 48/82)

12

Chang YH, Hsiao YM , Hu CC , Chang CH, Li CY , Steve W N Ueng, Chen MF. Synovial Fluid Interleukin-16 Contributes to Osteoclast Activation and Bone Loss Through the JNK/NFATc1 Signaling Cascade in Patients With Periprosthetic Joint Infection. Int J Mol Sci. 2020 Apr; 21(8): 2904. (SCI, IF: 5.923, Biochemistry & Molecular Biology, Rank: 67/298) (First author)

13

MN Hsu, KL Huang, FJ Yu, PL Lai, AV Truong, MW Lin, Nuong Thi Kieu Nguyen, CC Shen, SM Hwang, Chang YH* , YC Hu. Coactivation of Endogenous Wnt10b and Foxc2 by CRISPR Activation Enhances BMSC Osteogenesis and Promotes Calvarial Bone Regeneration. Mol Ther. 2020 Feb 5; 28(2):441-451. (SCI, IF:11.454, Biotechnology & Applied Microbiology, Rank: 11/140)

14

Hsu MN, Chang YH, Truong VA, Lai PL, Nguyen TKN, Hu YC. CRISPR technologies for stem cell engineering and regenerative medicine. Biotechnol Adv. 2019 Dec; 37(8):107447. (SCI, IF: 14.227, Biotechamology & Applied microbiology, Rank: 4/159) (Co-first author)

15

Chen MF, Chang CH, Hu CC, Wu YY, Chang YH*, and S. W. N. Ueng *†. Periprosthetic Joint Infection Caused by Gram-Positive Versus Gram-Negative Bacteria: Lipopolysaccharide, but not Lipoteichoic Acid, Exerts Adverse Osteoclast-Mediated Effects on the Bone. J Clin Med. 2019 Sep; 8(9): 1289. (SCI, IF: 4.241, Medicine,Genral& Internal, Rank: 39/169) (Corresponding author)

16

Tsai Y, Chang CH, Lin YC, Lee SH, Hsieh PH, Chang YH*. Different microbiological profiles between hip and knee prosthetic joint infections. J Orthop Surg (Hong Kong). 2019 May-Aug; 27(2):2309499019847768. (SCI, IF: 1.118, Orthopedics, Rank: 70/82) (Corresponding author)

17

Chen MF, Chang CH, Chuan CN, Hsieh PH, Shih HN, S. W. N. Ueng and Chang YH*. Rapid analysis of bacterial composition in prosthetic joint infection by 16S rRNA metagenomic sequencing. Bone Joint Res. 2019 Aug; 8(8): 367–377. (SCI, IF: 5.853, Orthopedics, Rank: 4/82) (Corresponding author)

18

MF Chen, CH Chang, LY Yang, PH Hsieh, HN Shih, S. W. N. Ueng, and Chang YH*. Synovial fluid interleukin-16, interleukin-18, and CRELD2 as novel biomarkers of prosthetic joint infections. Bone Joint Res. 2019 Apr; 8(4): 179–188. (SCI, IF: 5.853, Orthopedics, Rank: 4/82) (Corresponding author)

19

Hsin Yi Lo, Uang Hung, Chang YH*. Comparison of Different Venous Thromboembolism Prophylaxis Options in Patients after Total Knee Replacement. Formosan Joural of Medicine. 2019 Mar; 23(2): 173-181. (Corresponding author)

20

LY Sung, MY Wu, MW Lin, MN Hsu, VA Truong, CC Shen, Yi Tu, KY Hwang, AP Tu, Chang YH*, YC Hu. Combining orthogonal CRISPR and CRISPRi systems for genome engineering and metabolic pathway modulation in Escherichia coli. Biotechnology Bioengeering. 2019 Jan; 116(5):1066-1079. (SCI, IF: 4.53, Biotechnology & Applied Microbiology, Rank: 44/159) (Corresponding author)
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