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5163Cases

2025-09-15 - 2031-12-31

Phase III

Active
An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)
  • Condition/Disease

    Pulmonary Arterial Hypertension

  • Test Drug

    Injectables

Participate Sites
2Sites

Recruiting2Sites

2025-11-11 - 2030-12-31

Phase II/III

Active
A Phase 2b/3, Randomized, Double-Blind Study to Investigate the Efficacy, Safety, and Tolerability of Ponsegromab (PF-06946860) Compared With Placebo Both With Background First-Line Chemotherapy in Adult Participants With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma
  • Condition/Disease

    Cachexia 、Metastatic Pancreatic Ductal Adenocarcinoma

  • Test Drug

    Injectable

Participate Sites
5Sites

Not yet recruiting5Sites

2025-11-01 - 2027-08-22

Phase II

Not yet recruiting
A Phase 2, Double-blind, Placebo-Controlled Study to Evaluate LY3537021 for the Treatment of Chemotherapy-Induced Nausea and Vomiting in Adult Participants With Malignant Disease
  • Condition/Disease

    Nausea 、Vomiting 、Drug-Related Side Effects and Adverse Reactions 、Neoplasms

  • Test Drug

    subcutaneous injection

Participate Sites
5Sites

Recruiting5Sites

2025-10-01 - 2029-03-27

Others

Not yet recruiting
A Multi-Centre, Single Arm, Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of GSK4527226 (AL101) in Participants With Early Alzheimer's Disease
  • Condition/Disease

    Alzheimer's Disease

  • Test Drug

    Injectable

Participate Sites
3Sites

Recruiting3Sites

2025-09-30 - 2033-12-31

Phase II

Not yet recruiting
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of V940 in Combination With Pembrolizumab and Chemotherapy as First-Line Treatment for Participants With Metastatic Squamous NSCLC (INTerpath-013)
  • Condition/Disease

    Squamous Non-small Cell Lung Cancer

  • Test Drug

    Injectables

Participate Sites
6Sites

Recruiting6Sites

2025-10-01 - 2028-12-31

Phase I/II

Not yet recruiting
An Open-label, Multicenter, Phase 1/2 Study Exploring the Safety and Efficacy of ABT-301 in Combination With Tislelizumab and Bevacizumab in Participants With Proficient Mismatch Repair (pMMR)/Non-Microsatellite Instability-High (Non-MSI-H) Locally Advanced or Metastatic Colorectal Cancer (mCRC)
  • Condition/Disease

    Colorectal Cancer (Diagnosis) 、Colorectal Cancer Metastatic、 Colorectal Cancer (CRC)、 Immunotherapy

  • Test Drug

    Capsules Intravenous infusion Intravenous infusion

Participate Sites
7Sites

Recruiting7Sites