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Developmental Phase

  • Phase I

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  • Phase II

  • Phase II/III

  • Phase III

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Trial Status

  • Not yet recruiting

  • Active

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  • Not yet recruiting

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The expected start time interval of the test

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Trial Applicant

  • Hospital/Foundation

  • Pharmaceutical/Biopharmaceutical company

  • Contract Research Organization

Important Roles

  • Asia Regional PI

  • Taiwan National PI

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Audit by Sponsors/CRO

  • Sponsors

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Investigator-initiated trial(IIT)

  • Yes

Filters

Taipei Veterans General Hospital

List

2394Cases

2020-05-01 - 2025-12-31

Phase II

Completed
A Phase II, Safety, and Efficacy Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Patients With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

  • Condition/Disease

    Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

  • Test Drug

    Tiragolumab/TECENTRIQ (Atezolizumab)

Participate Sites
5Sites

Recruiting5Sites

2020-12-01 - 2025-12-31

Phase II

Active
A Phase II, Randomized,Open-Label, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Compared with physician's choice of endocrine monotherapy in Patients with Previously treated Estrogen Receptor Positive, HER2 Negative Locally Advanced or Metastatic Breast Cancer.

  • Condition/Disease

    Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

  • Test Drug

    GDC-9545 Anastrozole Fulvestrant Letrozole Exemestane

Participate Sites
5Sites

Recruiting5Sites

2021-06-01 - 2031-12-24

Phase III

Active
A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF ADJUVANT ATEZOLIZUMAB OR PLACEBO AND TRASTUZUMAB EMTANSINE FOR HER2-POSITIVE BREAST CANCER AT HIGH RISK OF RECURRENCE FOLLOWING PREOPERATIVE THERAPY　

  • Condition/Disease

    主要療效目的 本試驗的主要療效目的乃是根據下列指標，評估 atezolizumab 併用trastuzumab emtansine 相較於安慰劑加上 trastuzumab emtansine 的療效： IDFS，定義為自隨機分配

  • Test Drug

    注射液劑

Participate Sites
6Sites

Recruiting6Sites

2022-06-01 - 2032-12-31

Phase III

Active
A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Giredestrant in Combination With Phesgo Versus Phesgo After Induction Therapy With Phesgo + Taxane in Patients With Previously Untreated HER2-Positive, Estrogen Receptor-Positive Locally-Advanced or Metastatic Breast Cancer

  • Condition/Disease

    Locally Advanced or Metastatic Breast Cancer

  • Test Drug

    GiredestrantPhesgo (1200/600 mg)Phesgo (600/600 mg)

Participate Sites
5Sites

Recruiting5Sites

2021-01-01 - 2025-12-31

Phase II

Active
A Phase II, Randomized, Double Blind Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Patients With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck

  • Condition/Disease

    Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck

  • Test Drug

    Atezolizumab Tiragolumab

Participate Sites
3Sites

Not yet recruiting3Sites

2019-11-01 - 2028-12-31

Phase III

Active
A Phase III, Multicenter, Randomized, Open-Label Study of Atezolizumab (Anti-PD-L1 Antibody) Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation

  • Condition/Disease

    Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation

  • Test Drug

    Atezolizumab, Bevacizumab

Participate Sites
5Sites

Recruiting5Sites

2023-03-01 - 2027-12-31

Others

Active
A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

  • Condition/Disease

    Metastatic Colorectal Cancer

  • Test Drug

    AtezolizumabTiragolumabInavolisibBevacizumabRO7435846(GDC-6036)CetuximabFluorouracilfolinic acid(Calcium Folinate)OxaliplatinIrinotecan

Participate Sites
3Sites

Not yet recruiting3Sites

2020-09-01 - 2027-06-30

Phase III

Active
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Atezolizumab With or Without Tiragolumab (Anti-TIGIT Antibody) in Patients With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy

  • Condition/Disease

    Esophageal Squamous Cell Carcinoma

  • Test Drug

    AtezolizumabTiragolumab

Participate Sites
6Sites

Not yet recruiting1Sites

Recruiting5Sites

2020-09-01 - 2026-12-31

Phase III

Active
A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Patients With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

  • Condition/Disease

    Esophageal Squamous Cell Carcinoma

  • Test Drug

    Tiragolumab ；Atezolizumab

Participate Sites
4Sites

Recruiting4Sites

2024-10-01 - 2035-12-31

Phase II

Active

  • Condition/Disease

  • Test Drug

Participate Sites
3Sites

Not yet recruiting1Sites

Recruiting2Sites

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