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2252Cases

2025-02-01 - 2027-12-31

Phase II

Completed
A randomized, blinded, placebo-controlled phase 2 trial evaluating the safety, tolerability, quantitative pharmacology, and efficacy (MAGIC) of DNTH103 in adult patients with generalized myasthenia gravis.
  • Condition/Disease

    ● Evaluate the safety and tolerability of DNTH103 in patients with generalized myasthenia gravis (gMG) up to week 13.

  • Test Drug

    DNTH103 150 mg/mL

Participate Sites
8Sites

Recruiting8Sites

2026-07-01 - 2029-05-31

Phase III

Active
A Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression
  • Condition/Disease

    Depressive Disorder, Treatment-Resistant

  • Test Drug

    鼻用噴液劑 鼻用噴液劑

Participate Sites
6Sites

Not yet recruiting4Sites

Recruiting2Sites

2026-07-24 - 2032-07-21

Phase II/III

Not yet recruiting
A PHASE 2/3 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC GASTRIC, GASTROESOPHAGEAL JUNCTION, OR ESOPHAGEAL ADENOCARCINOMA
  • Condition/Disease

    Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma

  • Test Drug

    注射劑 注射劑 注射劑 注射劑 錠劑 注射劑 錠劑

Participate Sites
3Sites

Not yet recruiting3Sites

2026-08-01 - 2035-12-31

Phase III

Not yet recruiting
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
  • Condition/Disease

    Alzheimer's Disease

  • Test Drug

    注射液劑

Participate Sites
8Sites

Not yet recruiting1Sites

2017-02-01 - 2022-12-20

Phase III

Completed
An Open-label Long-term Extension Safety Study of Esketamine Nasal Spray in Treatment-resistant Depression
  • Condition/Disease

    Depressive Disorder, Treatment-Resistant

  • Test Drug

    ESKETAMINE

Participate Sites
6Sites

Terminated5Sites

Study ended1Sites

2017-01-22 - 2023-12-22

Phase III

Completed
A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Ulcerative Colitis
  • Condition/Disease

    Ulcerative Colitis

  • Test Drug

    Filgotinib (GS-6034) Filgotinib (GS-6034)

Participate Sites
8Sites

Terminated4Sites

Study ended1Sites

2017-01-17 - 2020-09-30

Phase III

Completed
A RANDOMIZED, MULTICENTER, OPEN-LABEL, PHASE 3 STUDY OF NIVOLUMAB PLUS IPILIMUMAB VERSUS OXALIPLATIN PLUS FLUOROPYRIMIDINE IN SUBJECTS WITH PREVIOUSLY UNTREATED ADVANCED OR METASTATIC GASTRIC OR GASTROESOPHAGEAL JUNCTION CANCER
  • Condition/Disease

    Gastric Cancer,Gastroesophageal Junction Cancer

  • Test Drug

    Nivolumab/Ipilimumab/Oxaliplatin/Fluorouracil/Leucovorin/Capecitabine

Participate Sites
2Sites

Terminated1Sites

Study ended1Sites