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Developmental Phase

  • Phase I

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The expected start time interval of the test

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Investigator-initiated trial(IIT)

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Recruiting

List

38Cases

2022-01-01 - 2026-03-31

Phase II

Active

  • Condition/Disease

  • Test Drug

Participate Sites
6Sites

Recruiting4Sites

Terminated2Sites

2021-11-01 - 2022-04-29

Phase II

  • Condition/Disease

  • Test Drug

Participate Sites
4Sites

Not yet recruiting3Sites

Recruiting1Sites

2017-02-01 - 2019-06-30

Others

A Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Dose and Multiple Doses of GSK3389404 in Chronic Hepatitis B Subjects

  • Condition/Disease

    The plan includes adult male and female CHB subjects aged 18 to 70 (inclusive) who are not currently receiving CHB treatment. Part 1 (Groups A, B, C, and D) will include HBeAg-positive subjects, while Part 1 (Group C1) will include HBeAg-negative subjects. After completing part 1 of the administration (after reviewing the safety, tolerability, PK and PD differences between HBeAg status), the specific CHB group included in part 2 will be determined

  • Test Drug

    GSK3389404

Participate Sites
9Sites

Recruiting8Sites

2020-12-02 - 2022-07-26

Phase II

Phase llb Multi=Center, Randomised, Partial-Blind Parallel Cohort Study to Assess the Efficacy a and Safety of Treatment with GSK3228836 in Participants with Chronic Hepatitis Z Virus(B-Clear)nd Safety

  • Condition/Disease

    Patients with chronic hepatitis B virus

  • Test Drug

    GSK3228836

Participate Sites
4Sites

Recruiting4Sites

2019-07-05 - 2022-03-21

Phase I

A Phase 1b, Open-label, Multi-center Study to Evaluate the Safety, Tolerability and Activity of GS-9688 in Special Populations of Subjects with Chronic Hepatitis B

  • Condition/Disease

    Chronic Hepatitis B

  • Test Drug

    GS-9688 Filmed-coated Tablets

Participate Sites
5Sites

Recruiting5Sites

2020-10-01 - 2023-11-21

Phase II

A Phase 2b Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis.

  • Condition/Disease

    Nonalcoholic Steatohepatitis

  • Test Drug

    MK-3655

Participate Sites
7Sites

Not yet recruiting3Sites

Recruiting1Sites

Terminated3Sites

2019-12-01 - 2022-09-02

Phase II

A randomized, double-blind, parallel-group, multicenter study to assess efficacy, safety, and tolerability of oral tropifexor (LJN452) & licogliflozin (LIK066) combination therapy and each monotherapy compared with placebo, for treatment of adult participants with nonalcoholic steatohepatitis (NASH) and liver fibrosis (ELIVATE).

  • Condition/Disease

    Non Alcoholic Steatohepatitis (NASH)

  • Test Drug

    LJN452/LIK066

Participate Sites
3Sites

Not yet recruiting1Sites

Recruiting2Sites

2023-02-15 - 2025-06-30

Phase I

A Phase 1a/1b Study to Evaluate the Safety and Tolerability of Repeated Doses of Nonreplicating Arenavirus Vector Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B (CHB)

  • Condition/Disease

    Chronic Hepatitis B

  • Test Drug

    GS-2829GS-6779

Participate Sites
10Sites

Recruiting10Sites

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