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79Cases

2025-01-15 - 2032-12-01

Active
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  • Condition/Disease

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  • Test Drug

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Participate Sites
5Sites

Recruiting5Sites

2025-02-28 - 2032-06-30

Phase III

Active
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  • Condition/Disease

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  • Test Drug

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Participate Sites
13Sites

Recruiting13Sites

2025-03-01 - 2029-12-31

Others

Active
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  • Condition/Disease

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  • Test Drug

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Participate Sites
6Sites

Recruiting6Sites

2025-06-01 - 2025-11-03

Phase III

Not yet recruiting
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  • Condition/Disease

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  • Test Drug

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Participate Sites
11Sites

Recruiting11Sites

2025-06-01 - 2029-06-30

Phase III

Active
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  • Condition/Disease

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  • Test Drug

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Participate Sites
7Sites

Recruiting7Sites

2025-04-01 - 2033-01-20

Active
A phase 3, multicenter, randomized, open-label trial evaluating trastuzumab deruxtecan plus pembrolizumab versus platinum-based chemotherapy plus pembrolizumab as first-line therapy in participants with locally advanced, unresectable or metastatic HER2 overexpression and PD-L1 TPS <50% non-squamous non-small cell lung cancer (DESTINY-Lung06).
  • Condition/Disease

    The efficacy of T-DXd with pembrolizumab versus platinum-based chemotherapy with pembrolizumab was compared using PFS as assessed by BICR. PFS was defined as the time interval elapsed from the date of randomization to the date of radiographic disease progression or death from any cause. Tumor response was assessed by BICR tumor scans and determined using the Solid Tumor Response Assessment Criteria, version 1.1 (RECIST v1.1).

  • Test Drug

    Trastuzumab Deruxtecan

Participate Sites
9Sites

Recruiting9Sites