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Developmental Phase

  • Phase I

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  • Phase II

  • Phase II/III

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Trial Status

  • Not yet recruiting

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Recruitment Status

  • Not yet recruiting

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  • Stop recruiting

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Trial scale

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The expected start time interval of the test

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Trial Applicant

  • Hospital/Foundation

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  • Contract Research Organization

Important Roles

  • Asia Regional PI

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Audit by Sponsors/CRO

  • Sponsors

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Investigator-initiated trial(IIT)

  • Yes

Filters

許恒誠

Recruiting

List

5Cases

2025-02-01 - 2033-12-31

Phase III

Active
A phase 3, randomized, open-label, multicenter trial was conducted in patients with platinum-sensitive recurrent ovarian cancer to evaluate the efficacy and safety of sacituzumab tirumotecan (MK-2870) maintenance therapy with or without bevacizumab compared to standard care after second-line platinum-based doublet chemotherapy (TroFuse-022/ENGOT-ov84/GOG-3103).

  • Condition/Disease

    Part 1: (1) Adverse events (AEs) (2) Discontinuation of trial treatment due to AEs Part 2: (1) PFS: Time from randomization to the first recorded disease progression or death from any cause, whichever occurs first.

  • Test Drug

    Dexamethasone MK-2870 MVASI

Participate Sites
5Sites

Recruiting5Sites

2025-04-01 - 2032-12-31

Phase III

Active
A phase 3, randomized, open-label, multicenter trial was conducted in mismatched patients with intact endometrial cancer to compare the efficacy and safety of sacituzumab tirumotecan (Sac-TMT, MK-2870) plus pembrolizumab versus pembrolizumab alone as first-line maintenance therapy (TroFuse-033/GOG-3119/ENGOT-en29).

  • Condition/Disease

    Progression-free survival (PFS): Time from randomization to the first recorded disease progression or death from any cause, whichever occurs first. Overall survival (OS): Time from randomization to death from any cause.

  • Test Drug

    Pembrolizumab (MK-3475) Sacituzumab Tirumotecan (MK-2870)

Participate Sites
5Sites

Recruiting5Sites

2026-07-01 - 2030-12-31

Phase I/II

Not yet recruiting

  • Condition/Disease

  • Test Drug

Participate Sites
2Sites

Recruiting2Sites

2026-01-16 - 2033-12-31

Phase III

Active

  • Condition/Disease

  • Test Drug

Participate Sites
5Sites

Recruiting5Sites

2024-02-12 - 2028-11-18

Phase II/III

Active

  • Condition/Disease

  • Test Drug

Participate Sites
7Sites

Recruiting7Sites

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