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Developmental Phase

  • Phase I

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  • Phase II

  • Phase II/III

  • Phase III

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Trial Status

  • Not yet recruiting

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The expected start time interval of the test

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Trial Applicant

  • Hospital/Foundation

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Important Roles

  • Asia Regional PI

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  • Sponsors

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Investigator-initiated trial(IIT)

  • Yes

Filters

彭成元

Recruiting

List

40Cases

2021-01-04 - 2025-12-31

IIT

Others

Active
An open-label, multicenter, randomized, active control study, comparing P1101 monotherapy to entecavir monotherapy in patients with HBeAg-negative chronic hepatitis B under long-term nucleos(t)ide analogue therapy

  • Condition/Disease

    chronic hepatitis B virus infection

  • Test Drug

    Ropeginterferon alfa-2b (P1101)

Participate Sites
6Sites

Not yet recruiting1Sites

Recruiting5Sites

2022-07-01 - 2027-02-26

Phase II

Active

  • Condition/Disease

  • Test Drug

Participate Sites
8Sites

Not yet recruiting4Sites

Recruiting4Sites

2025-02-03 - 2029-12-23

Phase III

Not yet recruiting
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of TPST-1120 in Combination with Atezolizumab plus Bevacizumab Compared with Placebo plus Atezolizumab plus Bevacizumab in Patients with Unresectable or Metastatic Hepatocellular Carcinoma (HCC) Not Previously Treated with Systemic Therapy

  • Condition/Disease

    HCC

  • Test Drug

    TPST-1120

Participate Sites
6Sites

Recruiting6Sites

2020-10-01 - 2025-12-31

Phase II

Completed
A Phase 2, Multicenter, Randomized, Double-blind, Placebo‑controlled Study with Deferred Active Treatment to Investigate the Efficacy, Safety, and Pharmacokinetics of JNJ‑73763989 + Nucleos(t)ide Analog in Participants Co‑infected with Hepatitis B and Hepatitis D Virus

  • Condition/Disease

    Patients infected with both hepatitis B and D viruses

  • Test Drug

    JNJ-73763989

Participate Sites
3Sites

Recruiting3Sites

2021-01-18 - 2023-08-31

Phase II

Completed
A Phase 2, Open-label, Single-arm, Multicenter Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Treatment With JNJ-73763989, JNJ-56136379, Nucleos(t)ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Patients With Chronic Hepatitis B Virus Infection

  • Condition/Disease

    Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

  • Test Drug

    JNJ-73763989 JNJ-56136379 JNJ-56136379

Participate Sites
3Sites

Recruiting3Sites

2020-09-01 - 2024-07-05

Phase II

Completed
A Phase 2, Randomized, Open-label, Multicenter Study to Evaluate Efficacy, Pharmacokinetics, Safety, and Tolerability of Response-guided Treatment With JNJ-73763989 + JNJ-56136379 + Nucleos(t)Ide Analog Regimen With or Without Pegylated Interferon Alpha-2a in Treatment-naive Patients With HBeAg Positive Chronic Hepatitis B Virus Infection and Normal ALT

  • Condition/Disease

    HBeAg Positive Chronic Hepatitis B Virus Infection

  • Test Drug

    JNJ-56136379JNJ-73763989JNJ-56136379

Participate Sites
4Sites

Recruiting4Sites

2025-04-01 - 2030-06-18

Phase III

Active
A Phase III, Randomised, Open-Label, Sponsor-Blinded, Multicentre Study of Rilvegostomig in Combination with Bevacizumab with or without Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma (ARTEMIDE-HCC01)

  • Condition/Disease

    Advanced Hepatocellular Carcinoma

  • Test Drug

    Rilvegostomig (AZD2936) Tremelimumab BEVACIZUMAB

Participate Sites
8Sites

Recruiting8Sites

2022-03-31 - 2027-12-31

Phase III

Active
A Phase III, Randomized, Open-Label, Sponsor-Blinded, Multicenter Study of Durvalumab in Combination With Tremelimumab ± Lenvatinib Given Concurrently With TACE Compared to TACE Alone in Patients With Locoregional Hepatocellular Carcinoma (EMERALD-3)

  • Condition/Disease

    Hepatocellular Carcinoma

  • Test Drug

    靜脈點滴注射劑 靜脈點滴注射劑

Participate Sites
6Sites

Recruiting6Sites

2018-11-30 - 2025-12-31

Phase III

Active
A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Transarterial Chemoembolization (TACE) in Combination With Either Durvalumab Monotherapy or Durvalumab Plus Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma (EMERALD-1)

  • Condition/Disease

    Locoregional Hepatocellular Carcinoma

  • Test Drug

    DURVALUMAB (IMFINZI, MEDI4736)

Participate Sites
10Sites

Recruiting9Sites

林錫銘
Linkou Chang Gung Medical Foundation

Digestive System Department

2023-09-01 - 2027-04-30

Phase II

Active
A Phase 2, Randomized Study to Evaluate the Optimized Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab for Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Patients Who Have Progressed After an Immune Checkpoint Inhibitor Containing Regimen in First-Line HCC

  • Condition/Disease

    Hepatocellular Carcinoma

  • Test Drug

    Budigalimab (ABBV-181)；Livmoniplimab (ABBV-151)

Participate Sites
9Sites

Not yet recruiting3Sites

Recruiting6Sites

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