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Clinical Trials List

Protocol NumberB9991046
NCT Number(ClinicalTrials.gov Identfier)NCT05059522
Active

2022-07-01 - 2027-12-31

Phase III

Not yet recruiting2

Recruiting2

Avelumab Master Protocol: An Open-label Continuation Study for Participants Continuing From Pfizer-sponsored Avelumab Clinical Studies.

  • Sponsor

  • Trial scale

    Multi-Regional Multi-Center

  • Update

    2026/02/01

Investigators and Locations

Principal Investigator Po-Jung Su

Co-Principal Investigator

The Actual Total Number of Participants Enrolled

0 Recruiting

Principal Investigator Chia-Chi Lin

Co-Principal Investigator

The Actual Total Number of Participants Enrolled

0 Recruiting

Principal Investigator Chao-Hsiang Chang 未分科

Co-Principal Investigator

The Actual Total Number of Participants Enrolled

0 Not yet recruiting

Principal Investigator Wen-Pin Su Division of Others -

Co-Principal Investigator

The Actual Total Number of Participants Enrolled

0 Not yet recruiting

Condition/Disease

Advanced Malignancies NS

Objectives

Provides continued treatment access, safety tracking, and, where applicable, overall survival tracking for eligible participants who continue to receive benefit from the trial intervention from the Pfizer-sponsored avelumab parent trial

Test Drug

Avelumab (MSB0010718C)PF-04518600 (OX-40)Utomilumab (PF-05082566)

Active Ingredient

Avelumab
PF-04518600
Utomilumab (PF-05082566)

Dosage Form

Solution for injection
Solution for injection
Solution for injection

Dosage

20mg/mL
10mg/ml
10mg/ml

Endpoints

Monitoring the safety and tolerability of investigational interventions

Inclution Criteria

Inclusion Criteria:

Any participant who is receiving study treatment and deriving significant clinical benefit or is in the safety and/or survival follow-up period in a Pfizer-sponsored Avelumab Parent Study.
Participants must agree to follow the reproductive criteria.
Participants must be willing and able to comply with all scheduled visits, treatment plan, and other study procedures.

Exclusion Criteria

Exclusion Criteria:

Female participants who are pregnant or breastfeeding.
Any medical reason that, in the opinion of the Investigator or Sponsor, precludes the participant from inclusion in the study.

The Estimated Number of Participants

  • Taiwan

    7 participants

  • Global

    300 participants