Clinical Trials List
2009-01-01 - 2013-12-31
Phase III
Terminated13
ICD-10I24.9
Acute ischemic heart disease, unspecified
ICD-9411.89
Other acute and subacute forms of ischemic heart disease
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in Addition to Standard of Care in Subjects With Acute Coronary Syndrome: Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA•CER)
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Trial Applicant
Merck Sharp & Dohme (I.A.) LLC
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Sponsor
Merck Sharp & Dohme Corp.
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Trial scale
Multi-Regional Multi-Center
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Update
2025/08/20
Investigators and Locations
Co-Principal Investigator
- 李文興 Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 楊正旭 Division of Cardiovascular Diseases
- 陳建仁 Division of Cardiovascular Diseases
- 方志元 Division of Cardiovascular Diseases
- 葉漢根 Division of Cardiovascular Diseases
- Shyh-Ming Chen Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 張盛雄 Division of Cardiovascular Diseases
- 劉俊傑 Division of Cardiovascular Diseases
- 蘇正煌 Division of Cardiovascular Diseases
- 李應湘 Division of Cardiovascular Diseases
- 藍偉仁 Division of Cardiovascular Diseases
- 蔡政廷 Division of Cardiovascular Diseases
- 洪大川 Division of Cardiovascular Diseases
- 陳俊延 Division of Cardiovascular Diseases
- Ping-Ing Lee Division of Cardiovascular Diseases
- 侯嘉殷 Division of Cardiovascular Diseases
- 林柏霖 Division of Cardiovascular Diseases
- 蔡瑞鵬 Division of Cardiovascular Diseases
- 吳懿哲 Division of Cardiovascular Diseases
- 顏志軒 Division of Cardiovascular Diseases
- 陳正熙 Division of Cardiovascular Diseases
- 彭明正 Division of Cardiovascular Diseases
- 郭任遠 Division of Cardiovascular Diseases
- 林慧君 Division of Cardiovascular Diseases
- Hung-I Yeh Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- CHIA-TI TSAI Division of General Internal Medicine
- YEN-HUNG LIN Division of Cardiovascular Diseases
- Tzung-Dau Wang Division of General Internal Medicine
- LIAN-YU LIN Division of General Internal Medicine
- 陳明豐 Division of General Internal Medicine
- Yi-Chih Wang Division of General Internal Medicine
- MAO-HSIN LIN Division of Cardiovascular Diseases
- 張博淵 Division of General Internal Medicine
- - - Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 蔡青峰 Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 王宇澄 Division of Cardiovascular Diseases
- 謝禮全 Division of Cardiovascular Diseases
- Ping-Han Lo Division of Cardiovascular Diseases
- Shih-Sheng Chang Division of Cardiovascular Diseases
- 陳業鵬 Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 吳文憲 Division of General Internal Medicine
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- 王鑑忠 Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
The Actual Total Number of Participants Enrolled
0 Terminated
Co-Principal Investigator
- Po-Chao Hsu Division of Cardiovascular Diseases
- Wei-Chung Tsai Division of Cardiovascular Diseases
- Ye-Hsu Lu Division of Cardiovascular Diseases
Co-Principal Investigator
- 彭明正 Division of Cardiovascular Diseases
- Hung-I Yeh Division of Cardiovascular Diseases
- 顏志軒 Division of Cardiovascular Diseases
- 李應湘 Division of Cardiovascular Diseases
- 林柏霖 Division of Cardiovascular Diseases
- 劉俊傑 Division of Cardiovascular Diseases
- 郭任遠 Division of Cardiovascular Diseases
- 陳俊延 Division of Cardiovascular Diseases
- 侯嘉殷 Division of Cardiovascular Diseases
- Ping-Ing Lee Division of Cardiovascular Diseases
- 洪大川 Division of Cardiovascular Diseases
- 吳懿哲 Division of Cardiovascular Diseases
- 蔡政廷 Division of Cardiovascular Diseases
- 蔡瑞鵬 Division of Cardiovascular Diseases
- 蘇正煌 Division of Cardiovascular Diseases
- 林慧君 Division of Cardiovascular Diseases
The Actual Total Number of Participants Enrolled
0 Terminated
Condition/Disease
Objectives
Test Drug
Active Ingredient
Dosage Form
Dosage
Endpoints
Inclution Criteria
current symptoms of cardiac ischemia (chest pain leading to cardiac ischemia or heart attack)
AND
either of the following:
concurrent elevation of troponin I or T, or of creatine kinase - myocardial band (CK-MB) to a level above the upper limit of normal, OR
concurrent appropriate electrocardiographic evidence
AND
any one (or more) of the following:
age >= 55 years
documented history of prior heart attack or coronary revascularization (eg, angioplasty [PCI], coronary artery replacement [CABG])
diabetes (documented use of insulin or oral hypoglycemic[s])
documented history of peripheral arterial disease
Exclusion Criteria
any bleeding disorder or abnormality
sustained severe hypertension or valvular heart disease
current or recent platelet count <100,000 mm^3
planned or ongoing treatment with a blood thinning medication
pregnancy
any significant medical or physiological condition or abnormality that could put the subject at increased risk or limit the subject's ability to participate for the duration of the study
The Estimated Number of Participants
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Taiwan
300 participants
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Global
participants
